Sulfoconjugation of catecholamines, nutrition, and hypertension.

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Sulfoconjugation of catecholamines, nutrition, and hypertension.

Sulfoconjugation is an important metabolic pathway determining the fate and potential cardiovascular action of ingested phenolic substances. Among the three catecholamines, dopamine (DA) is to the highest degree sulfoconjugated and has the highest affinity toward the phenolsulfotransferase (PST). The concentration of some sulfated catecholamines, particularly of DA sulfate, increases following ...

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Catecholamines and hypertension.

Ever since the demonstration that the active principle in the adrenal medulla can raise blood pressure (Oliver & Schafer, 1895), catecholamines have been implicated in the hypertensive diseases. The identity of noradrenaline as the neurotransmitter of sympathetic nerves (von Euler, 1946) and the demonstration that an injection of this catecholamine can produce cardiovascular changes similar to ...

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Plasma Catecholamines and Essential Hypertension

Of 78 comparative studies of plasma catecholamines in patients with essential hypertension and in normotensive controls, most reported higher catecholamine levels in the hypertensives, although only about 40% of the studies were positive (reporting statistically significant hypertensivenormotensive differences). Although there was dramatic variability in catecholamine values within and across s...

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Free and conjugated catecholamines in human hypertension.

1. Noradrenaline and adrenaline in the adrenal vein of essential hypertensive patients are almost exclusively (99%) unconjugated or free. However only 17% of dopamine is free, the rest is conjugated. The further the site of sampling from the adrenal vein the closer come the free catecholamines to their normal peripheral venous proportion (noradrenaline + adrenaline 20%, dopamine less than 1% of...

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[Arterial hypertension and increased urinary catecholamines].

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ژورنال

عنوان ژورنال: Hypertension

سال: 1982

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.4.5_pt_2.iii93